Gut On A Bead - Deciphering the Gut Microbiome

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Programme Social programme Plenary speakers Keynote speakers 1st EuroCarb Young Researcher (ECYR) Workshop CarboMet Workshop Mini symposium: Glycobiology at the LUMC and beyond Favourites/Agenda

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1st EuroCarb Young Researcher (ECYR) Workshop

CarboMet Workshop

Mini symposium: Glycobiology at the LUMC and beyond

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Gut On A Bead - Deciphering the Gut Microbiome

Tim Leenders

1 Utrecht University, Utrecht, Nederland

A new widely applicable method for investigating the activity of our microbiome in the gut is shown. By coupling known O-glycan epitopes to a cleavable linker attached to magnetic beads, we hope to decipher the activity of microbes in our gut in different contexts. Through use of isotopes and advanced mass spectrometry methods, quantitative analysis of degraded O-glycan epitopes can be achieved.

Using this data, we aim to investigate issues that arise from a disturbed microbiome (for instance inflammatory bowel disease (IBD)) and study the dependency of commensal and pathogenic bacteria to our gut and other microbiota. This information could prove useful when analyzing a patient experiencing symptoms in the gut.

Schematic overview of the process to obtaining information into bacterial activity in the gut.

Contact eurocarb@eurocarb2019.com for general questions about EUROCARB2019, or codee@eurocarb2019.com for scientific questions.

Leiden University / Leiden Institute of Chemistry lic.leidenuniv.nl

European Carbohydrate Organisation

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