Block Polysaccharides

Session: 
PS2 Poster session 2 Even numbers
Code: 
P40
Location (hall): 
Foyer
Start/end time: 
Tuesday, July 2, 2019 - 15:45 to 17:15
Bjørn
Christensen

Bjørn E. Christensen1

1NTNU-Norwegian University Of Science And Technology, Trondheim, Norway

Certain plant polysaccharides such as alginates and pectins have a modular structure determined by the biosynthesis. The modular structure of alginates, their analysis, and their importance in the gelation to form biomaterials will be briefly discussed.

A second approach to modular polysaccharides involves covalently assembling oligosaccharides from different sources to form hybrid block polysaccharides. This allows the design of new biopolymers with multiple built-in properties analogous to synthetic block polymers. We have explored the use of two key bioconjugation methods often used in glycosciences, namely dioxyamine and dihydrazide chemistry to form a range of diblock polysaccharides based on alginate, chitin, chitosan, dextran and β-1,3-glucans. These studies also include the use of 2-picoline borane as reductant. Recent results will be presented.

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