Block Polysaccharides

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Programme Social programme Plenary speakers Keynote speakers 1st EuroCarb Young Researcher (ECYR) Workshop CarboMet Workshop Mini symposium: Glycobiology at the LUMC and beyond Favourites/Agenda

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1st EuroCarb Young Researcher (ECYR) Workshop

CarboMet Workshop

Mini symposium: Glycobiology at the LUMC and beyond

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Block Polysaccharides

Bjørn E. Christensen 1

1 NTNU-Norwegian University Of Science And Technology, Trondheim, Norway

Certain plant polysaccharides such as alginates and pectins have a modular structure determined by the biosynthesis. The modular structure of alginates, their analysis, and their importance in the gelation to form biomaterials will be briefly discussed.

A second approach to modular polysaccharides involves covalently assembling oligosaccharides from different sources to form hybrid block polysaccharides. This allows the design of new biopolymers with multiple built-in properties analogous to synthetic block polymers. We have explored the use of two key bioconjugation methods often used in glycosciences, namely dioxyamine and dihydrazide chemistry to form a range of diblock polysaccharides based on alginate, chitin, chitosan, dextran and β-1,3-glucans. These studies also include the use of 2-picoline borane as reductant. Recent results will be presented.

Contact eurocarb@eurocarb2019.com for general questions about EUROCARB2019, or codee@eurocarb2019.com for scientific questions.

Leiden University / Leiden Institute of Chemistry lic.leidenuniv.nl

European Carbohydrate Organisation

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